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David A. Sinclair, Matthew D. LaPlante Books

1 book·~10 min total read

David A. Sinclair is a professor of genetics at Harvard Medical School and a leading researcher in the field of aging and longevity.

Known for: Lifespan: Why We Age—and Why We Don't Have To

Books by David A. Sinclair, Matthew D. LaPlante

Lifespan: Why We Age—and Why We Don't Have To

Lifespan: Why We Age—and Why We Don't Have To

life_science·10 min read

In this groundbreaking work, Harvard geneticist David A. Sinclair argues that aging is a disease—and that it is treatable. Drawing on decades of research, Sinclair explains the biological mechanisms of aging and presents scientific advances that could extend human lifespan and healthspan. The book explores how lifestyle, genetics, and emerging technologies can slow or even reverse aspects of aging, offering a vision of a future where growing old no longer means decline.

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Key Insights from David A. Sinclair, Matthew D. LaPlante

1

The Information Theory of Aging

The heart of my argument rests on what I call the Information Theory of Aging. Biology, at its core, is about information — not just genetic code but how that code is read and executed. Our DNA is astonishingly stable, like the hard drive storing the body’s instructions. Yet over time, the epigeneti...

From Lifespan: Why We Age—and Why We Don't Have To

2

The Role of Sirtuins and NAD+

In my lab, the quest to understand longevity led us to sirtuins — a family of genes that act as the guardians of cellular health. When I first began studying them, few could imagine their significance. Sirtuins regulate the body’s responses to stress and scarcity, maintaining genomic stability and e...

From Lifespan: Why We Age—and Why We Don't Have To

About David A. Sinclair, Matthew D. LaPlante

David A. Sinclair is a professor of genetics at Harvard Medical School and a leading researcher in the field of aging and longevity. He is known for his pioneering work on sirtuins and NAD+ metabolism. Matthew D. LaPlante is a journalist and associate professor of journalism at Utah State University...

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David A. Sinclair is a professor of genetics at Harvard Medical School and a leading researcher in the field of aging and longevity. He is known for his pioneering work on sirtuins and NAD+ metabolism. Matthew D. LaPlante is a journalist and associate professor of journalism at Utah State University, specializing in science communication.

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David A. Sinclair is a professor of genetics at Harvard Medical School and a leading researcher in the field of aging and longevity.

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